There is also the risk that veins may be damaged and that something nasty will develop, such as an abscess or a clot. However, there is no evidence to support this and it is possible that MXE will turn out to be as toxic as ketamine in this regard. Although there is little known about MXE we do know that it is chemically related to dissociative anaesthetics like ketamine and PCP.
The effects of MXE tend to be similar to ketamine effects, but are more intense and longer lasting and include:. MXE can make people feel very chilled out, relaxed and euphoric.
Others have reported being agitated. You could feel completely detached from your body and surroundings, putting yourself in danger of accidentally being hurt or being hurt by others. MXE can also cause involuntary eye movement, loss of balance and poor coordination, unsteadiness on your feet and slurred speech. These effects are not seen when people use ketamine. It normally takes 10 to 15 minutes for the effects of methoxetamine MXE to be felt, but sometimes it can take 60 to 90 minutes.
There have been no confirmed deaths from methoxetamine MXE and nobody knows the long-term risks of using MXE, and how similar the risks are to ketamine. But we do have a better idea of some of the short term risks:. So you could end up hurting yourself or being hurt by others. Compared to many other powder drugs, you only need to take a small amount of MXE to have a substantial effect. MXE is marketed as a replacement for ketamine , but without ketamine's harmful effect on the bladder.
However, there is no evidence to support this. It is possible that MXE will turn out to be as toxic as ketamine in this regard. It appears that MXE can make the heart beat faster than it should called tachycardia and increases blood pressure.
The effects of combining drugs — including over-the-counter or prescribed medications — can be unpredictable and dangerous. There is little evidence available on the effects of MXE when combined with other drugs. Anecdotal reports suggest that mixing MXE with alcohol , cannabis and antidepressants should be avoided.
There is limited evidence regarding MXE and dependence, however, experts believe that the similarity to ketamine means that it carries a comparable risk of dependence. While the Independent Scientific Committee on Drugs UK ranks ketamine as less harmful than other illicit drugs such as methamphetamine , heroin , cocaine or GHB , 13 some studies have indicated a high risk for tolerance and dependence. When used repeatedly and for extended periods, MXE seems to show signs of producing similar bladder and urinary tract problems to that of ketamine.
Ketamine-induced cystitis can become extremely serious and is a painful condition needing ongoing treatment. Not sure what you are looking for? Try our intuitive Path2Help tool and be matched with support information and services tailored to you. Kmax , M-ket , Mexxy. Last published: November 10, What is methoxetamine? Other types of dissociatives Ketamine Nitrous oxide.
How is it used? MXE is usually snorted, swallowed or injected. In small doses the following effects may occur and may last for up to 7 hours: euphoria empathy pleasant sensory experience dissociation vivid hallucinations introspection anti-depressant 2, 3, 5 Some adverse effects include: disorientation confusion dizziness anxiety rapid heart rate nausea paranoia vomiting slurring or difficulty speaking psychomotor agitation e. When people experience a spike in dopamine levels, it reinforces the desire to use again and the brain requires more and more of the drug to achieve feelings of pleasure.
The result: compulsive drug-seeking behavior. This can include spending large amounts of time seeking and using the drug and neglecting work and family responsibilities.
As there is very little information available, many addiction counselors and medical staff may not have even heard of the drug, let alone know about the effects. This may make forming a therapeutic relationship and effective addiction treatment for this drug particularly challenging. Once people have developed a dependence on or addiction to MXE, they are likely to experience symptoms of withdrawal if they suddenly stop taking the drug.
These symptoms can range from mild to serious and can impact the body and mind, including:. While there is no specific treatment for MXE addiction, there are some proven treatment options that could help you or someone you love. Treatment may include supervised detox, rehab inpatient, outpatient, or residential , cognitive-behavioral therapy, family therapy, support groups, relapse prevention, and medication for any co-occurring mental illnesses.
If you have a problem with MXE use, talk to your doctor. Together, you can figure out the right treatment to begin the road to lasting recovery. Don't wait to get help. The Substance Abuse and Mental Health Services Administration has a national helpline as well as an online treatment locator to find mental health services in your area. Learn the best ways to manage stress and negativity in your life. Phenomenon of new drugs on the Internet: the case of ketamine derivative methoxetamine.
Hum Psychopharmacol. Ketamine-like effects after recreational use of methoxetamine. Ann Emerg Med. Here today, gone tomorrow…and back again? A review of herbal marijuana alternatives K2, Spice , synthetic cathinones bath salts , kratom, Salvia divinorum, methoxetamine, and piperazines.
J Med Toxicol. Acute toxicity associated with the recreational use of the ketamine derivative methoxetamine. Eur J Clin Pharmacol. Your Privacy Rights. To change or withdraw your consent choices for VerywellMind. At any time, you can update your settings through the "EU Privacy" link at the bottom of any page.
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How to Recognize MXE MXE is typically produced in the form of a white or off-white powder and may be labeled "not intended for human consumption" or sold as a "research chemical. How to Recognize Signs of Drug Overdose. Effective Drug Addiction Treatment.
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